Pro Bone Morphogenetic Protein -2 Human Recombinant
Pro Bone Morphogenetic Protein -2 Human Recombinant is the precursor of BMP-2 which has 3 intramolecular cystein bridges is a homodimer, non-glycosylated, polypeptide chain containing 377 amino acids and having a molecular mass of 85,476 Dalton.
Pro Bone Morphogenetic Protein 2 is purified by proprietary chromatographic techniques.
Accession
Biological Activity
The ProBMP-2 Human Recombinant administration leads to ectopic bone formation in rats (Hillger et al., 2005).
Formulation
The Pro Bone Morphogenetic Protein -2 Human Recombinant was lyophilized in 0.1M K-HEPES pH 7.0 / Mannite.
Physical Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.
Purity
Greater than 98.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.
Solubility
It is recommended to reconstitute the lyophilized Pro Bone Morphogenetic Protein -2 Human Recombinant in sterile 18MΩ-cm H2O not less than 100ug/ml, which can then be further diluted to other aqueous solutions.
Source
Stability
Lyophilized Pro Bone Morphogenetic Protein -2 Human Recombinant although stable at room temperature for 3 weeks, should be stored desiccated below -18oC. Upon reconstitution Pro Bone Morphogenetic Protein -2 Human Recombinant should be stored at 4oC between 2-7 days and for future use below -18oC.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.
Synonyms
