Interferon-alpha 2b 20kd-Pegylated Human Recombinant
Interferon-a 2b Human Recombinant produced in E.coli is a single, non-glycosylated, polypeptide chain containing 165 amino acids and having a molecular mass of 19269 Dalton. The Pegylated IFN-a 2b is produced by attaching a 20kDa mPEG-aldehyde to the N-terminal IFN alpha-2b.
Interferon-a 2b is purified by proprietary chromatographic techniques.
Accession
Biological Activity
The specific activity as determined in a viral resistance assay using VSV-WISH cells was found to be 3,000,000 IU/mg.
Formulation
IFN-a 2b is supplied in solution (1.48mg/ml) containing 20mM Acetate Buffer (pH 6.0), 0.8%NaCl and 0.005% Polysorbate 80.
Physical Appearance
Colorless, clear and transparent solution.
Purity
Greater than 97.0% as determined by SEC-HPLC.
Source
Stability
IFN alpha-2b PEG should be stored refrigerated at 2¡ã to 8oC. Vials should be kept in their packaging to protect from light until the time of use.
Shaking and freezing should be avoided.
Synonyms
Interferon alpha 2b, IFNA, INFA2, MGC125764, MGC125765.
