Potency is determined by its ability to neutralize TNF-alpha mediated growth inhibition of A375 cells, corresponding to a Specific Activity of 17,000,000 IU/mg.
Each mg contains 1.6mg mannitol, 0.4 mg sucrose and 48 ug tromethamine.
Sterile Filtered White lyophilized (freeze-dried) powder.
Greater than 98.0% as determined by
(a) Analysis by RP-HPLC.
(c) Analysis by SDS-PAGE.
It is recommended to reconstitute the lyophilized TNFR in sterile 18MΩ-cm H2O not less than 100ug/ml, which can then be further diluted to other aqueous solutions.
Chinese Hamster Ovarian Cells (CHO).
Lyophilized Tumor Necrosis Factor Receptor although stable at room temperature for 3 weeks, should be stored desiccated below -18oC. Upon reconstitution TNFR should be stored at 4oC between 2-7 days and for future use below -18oC.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.
Tumor necrosis factor receptor superfamily member 1B,Tumor necrosis factor receptor 2, TNF-R2, Tumor necrosis factor receptor type II, p75, p80 TNF-alpha receptor, CD120b antigen, Etanercept, TBPII, TNFBR, TNFR80, TNF-R75, p75TNFR, TNF-R-II.
