$513.00Catalog Number: PTN378-1mgSize: 1mg

SERPINA3 Human

Alpha-1 AntiChymotrypsin Human

Human Alpha-1 AntiChymotrypsin produced from normal human serum having a molecular mass of 68kDa.

Accession

P01011

Formulation

Lyophilized from 0.02M NH4HCO3.

Human Virus Test

Starting material tested and found negative for HIV I & II antibodies, Hepatitis B surface antigen, and Hepatitis C antibodies.

Introduction

Alpha 1 ACT is an early-stage acute-phase plasma protein and a serpin that preferentially inactivates chymotrypsin, cathepsin G, and chymase. Alpha-1- ACT, a serine protease inhibitor, is tightly associated with amyloid plaques in Alzheimer's disease (AD) and in normal aged human and monkey brain.
Regulation of the serine proteases and serine protease inhibitors plays an important role in neuromuscular differentiation. Prostate specific antigen (PSA), a chymotrypsin-like serine protease, is predominantly complexed to Alpha-1-ACT.

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Purity

Greater than 99.0%.

Solubility

It is recommended to reconstitute the lyophilized human A1ACT in phosphate buffer pH > 7.0 containing 0.15M NaCl.

Source

Human Serum.

Stability

Human SERPINA3 although stable at room temperature for 3 weeks, should be stored between 2-8oC.

Synonyms

Alpha-1-antichymotrypsin, ACT, Cell growth-inhibiting gene 24/25 protein, SERPINA3, AACT, A1ACT, GIG24, GIG25, MGC88254.

Quantity

$513.00

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