$148.20Catalog Number: PTN413-100ugSize: 100ug

Cystatin C Human

Cystatin-C Human

Cystatins are a superfamily of cysteine proteinase inhibitors found in both plants and animals. They comprise a group of proteinase inhibitors, widely distributed in tissues and body fluids, and form tight complexes with cysteine proteases such as cathepsin B, H, L and S. Cystatin C, a secreted molecule of this family, is of interest from biochemical, medicine and evolutionary points of view. Cystatin C, with molecular weight of 13260 Da, is composed of 120 amino acids, lacks carbohydrate and has two disulfide bridges located near the carboxyl terminus. Cystatin C is increased in patients with malignant diseases, and is related to the insufficiency of renal function and appears to be a better marker than creatinine. On the other hand, low levels of cystatin C involve cause the breakdown of the elastic laminae and, subsequently, the atherosclerosis and abdominal aortic aneurysm.

Accession

P01034

Applications

ELISA, Western blotting.

Formulation

Lyophilized from 0.02M NH4HCO3. May contain traces of buffer salts.

Human Virus Test

Starting material tested and certified negative for HIV I & II antibodies, Hepatitis B surface antigen, and Hepatitis C antibodies.

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Purity

Greater than 96% as determined by SDS PAGE.

Solubility

Use of a 0.02M NH4HCO3 buffer is recommended.

Source

Human urine.

Stability

Human Cystatin-C although stable at 4oC for 1 week, should be stored at -15oC.
Please avoid freeze-thaw cycles.

Synonyms

Cystatin-C, Cystatin-3, Neuroendocrine basic polypeptide, Gamma-trace, Post-gamma-globulin, CST3, MGC117328.

Quantity

$148.20

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